leflunomide has been researched along with Cirrhoses, Experimental Liver in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, X | 1 |
| Yang, J | 1 |
| Li, J | 2 |
| Yao, HW | 1 |
| Chen, JQ | 1 |
| Xu, SY | 1 |
2 other studies available for leflunomide and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Accelerative effect of leflunomide on recovery from hepatic fibrosis involves TRAIL-mediated hepatic stellate cell apoptosis.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Blotting, Western; Cell Proliferation; Culture Media, Co | 2009 |
Inhibitory effect of leflunomide on hepatic fibrosis induced by CCl4 in rats.
Topics: Adjuvants, Immunologic; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachlo | 2004 |