leflunomide has been researched along with Central Nervous System Neoplasm in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Blood for pharmacokinetic analysis was obtained during the first cycle." | 2.71 | Pediatric phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU101. ( Adamson, PC; Balis, FM; Blaney, SM; Cropp, GF; Gillespie, AF; Hannah, AL; Kitchen, B; Murphy, RF; Patel, M; Whitcomb, PG; Widemann, BC, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, PC | 1 |
| Blaney, SM | 1 |
| Widemann, BC | 1 |
| Kitchen, B | 1 |
| Murphy, RF | 1 |
| Hannah, AL | 1 |
| Cropp, GF | 1 |
| Patel, M | 1 |
| Gillespie, AF | 1 |
| Whitcomb, PG | 1 |
| Balis, FM | 1 |
1 trial available for leflunomide and Central Nervous System Neoplasm
| Article | Year |
|---|---|
Pediatric phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU101.
Topics: Adolescent; Adult; Aniline Compounds; Antineoplastic Agents; Central Nervous System Neoplasms; Child | 2004 |