leflunomide has been researched along with Cardiac Remodeling, Ventricular in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, ZG | 1 |
| Zhang, X | 1 |
| Yuan, YP | 1 |
| Jin, YG | 1 |
| Li, N | 1 |
| Kong, CY | 1 |
| Song, P | 1 |
| Tang, QZ | 1 |
1 other study available for leflunomide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
A77 1726 (leflunomide) blocks and reverses cardiac hypertrophy and fibrosis in mice.
Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Heart | 2018 |