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leflunomide and Carcinoma, Neuroendocrine

leflunomide has been researched along with Carcinoma, Neuroendocrine in 1 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Carcinoma, Neuroendocrine: A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round blue cells, granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small (oat) cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
"Leflunomide (LFN) is a disease-modifying antirheumatic drug approved for the treatment of rheumatoid arthritis, and its active metabolite teriflunomide has been identified as a potential anticancer drug."1.39Leflunomide suppresses growth in human medullary thyroid cancer cells. ( Alhefdhi, A; Burke, JF; Chen, H; Kunnimalaiyaan, M; Redlich, A, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alhefdhi, A1
Burke, JF1
Redlich, A1
Kunnimalaiyaan, M1
Chen, H1

Other Studies

1 other study available for leflunomide and Carcinoma, Neuroendocrine

ArticleYear
Leflunomide suppresses growth in human medullary thyroid cancer cells.
    The Journal of surgical research, 2013, Volume: 185, Issue:1

    Topics: Antineoplastic Agents; Antirheumatic Agents; Basic Helix-Loop-Helix Transcription Factors; Biomarker

2013