leflunomide has been researched along with Carcinogenesis in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral squamous cell carcinoma (OSCC) is the most prevalent pathological cancer occurring in the head and neck area." | 1.46 | Leflunomide inhibits proliferation and tumorigenesis of oral squamous cell carcinoma. ( Cui, H; Fu, G; Qiu, Y; Ren, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, A | 1 |
| Fu, G | 1 |
| Qiu, Y | 1 |
| Cui, H | 1 |
1 other study available for leflunomide and Carcinogenesis
| Article | Year |
|---|---|
Leflunomide inhibits proliferation and tumorigenesis of oral squamous cell carcinoma.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Pro | 2017 |