leflunomide has been researched along with Canine Diseases in 5 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate efficacy and adverse effects of leflunomide for the treatment of naturally occurring immune-mediated polyarthritis (IMPA) in dogs." | 7.76 | Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008). ( Baker, TA; Colopy, SA; Muir, P, 2010) |
| "To evaluate efficacy and adverse effects of leflunomide for the treatment of naturally occurring immune-mediated polyarthritis (IMPA) in dogs." | 3.76 | Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008). ( Baker, TA; Colopy, SA; Muir, P, 2010) |
| " Data that were extracted from the medical records included signalment, body weight, underlying indication for leflunomide, dosage of leflunomide, treatment duration, concurrent medications, treatment response, and adverse events." | 1.46 | A Retrospective Study on the Safety and Efficacy of Leflunomide in Dogs. ( Lappin, MR; Legare, M; Sato, M; Veir, JK, 2017) |
| "The leflunomide treatment response rate was 93." | 1.43 | Efficacy of leflunomide for treatment of refractory inflammatory colorectal polyps in 15 Miniature Dachshunds. ( Eguchi, N; Fukushima, K; Igarashi, H; Kanemoto, H; Nakashima, K; Ohmi, A; Ohno, K; Takahashi, M; Tsujimoto, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tani, A | 1 |
| Seno, T | 1 |
| Yokoyama, N | 1 |
| Nakagawa, T | 1 |
| Tomiyasu, H | 1 |
| Goto-Koshino, Y | 1 |
| Tsujimoto, H | 2 |
| Ohno, K | 2 |
| Sato, M | 1 |
| Veir, JK | 1 |
| Legare, M | 1 |
| Lappin, MR | 1 |
| Fukushima, K | 1 |
| Eguchi, N | 1 |
| Kanemoto, H | 1 |
| Takahashi, M | 1 |
| Igarashi, H | 1 |
| Ohmi, A | 1 |
| Nakashima, K | 1 |
| Colopy, SA | 1 |
| Baker, TA | 1 |
| Muir, P | 1 |
| Gregory, CR | 1 |
| Stewart, A | 1 |
| Sturges, B | 1 |
| DeManvelle, T | 1 |
| Cannon, A | 1 |
| Ortega, T | 1 |
| Harb, M | 1 |
| Morris, RE | 1 |
5 other studies available for leflunomide and Canine Diseases
| Article | Year |
|---|---|
Comparison of the efficacy of cyclosporine and leflunomide in treating inflammatory colorectal polyps in miniature dachshunds.
Topics: Animals; Colonic Polyps; Cyclosporine; Dog Diseases; Dogs; Female; Immunosuppressive Agents; Japan; | 2020 |
A Retrospective Study on the Safety and Efficacy of Leflunomide in Dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Immune System Diseases; Immunosuppressive Agents; Isoxazoles; L | 2017 |
Efficacy of leflunomide for treatment of refractory inflammatory colorectal polyps in 15 Miniature Dachshunds.
Topics: Animals; Colonic Polyps; Dog Diseases; Dogs; Female; Immunosuppressive Agents; Intestinal Polyps; Is | 2016 |
Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Autoimmune Diseases; Dog Diseases; Dogs | 2010 |
Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy.
Topics: Aniline Compounds; Animals; Crotonates; Dog Diseases; Dogs; Female; Hydroxybutyrates; Immune System | 1998 |