leflunomide has been researched along with Cancer of Colon in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide, a drug which has been approved in Germany for the therapy of rheumatoid arthritis, inhibits the activity of several growth factors in vitro." | 1.31 | [Leflunomide reduces the angiogenesis score and tumor growth of subcutaneously implanted colon carcinoma cells in the mouse model]. ( Mall, JW; Myers, JA; Philipp, AW; Pollmann, C; Saclarides, TJ; Xu, X, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mall, JW | 1 |
| Myers, JA | 1 |
| Xu, X | 1 |
| Saclarides, TJ | 1 |
| Philipp, AW | 1 |
| Pollmann, C | 1 |
1 other study available for leflunomide and Cancer of Colon
| Article | Year |
|---|---|
[Leflunomide reduces the angiogenesis score and tumor growth of subcutaneously implanted colon carcinoma cells in the mouse model].
Topics: Administration, Oral; Animals; Capillaries; Cell Division; Colonic Neoplasms; HT29 Cells; Humans; In | 2002 |