leflunomide has been researched along with Breast Neoplasms in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zewail, M | 1 |
| E Gaafar, PM | 1 |
| Ali, MM | 1 |
| Abbas, H | 1 |
| Hubackova, S | 1 |
| Davidova, E | 1 |
| Boukalova, S | 1 |
| Kovarova, J | 1 |
| Bajzikova, M | 1 |
| Coelho, A | 1 |
| Terp, MG | 1 |
| Ditzel, HJ | 1 |
| Rohlena, J | 1 |
| Neuzil, J | 1 |
| Ghosh, S | 1 |
| Zheng, Y | 1 |
| Jun, X | 1 |
| Narla, RK | 1 |
| Mahajan, S | 1 |
| Navara, C | 1 |
| Mao, C | 1 |
| Sudbeck, EA | 1 |
| Uckun, FM | 1 |
3 other studies available for leflunomide and Breast Neoplasms
| Article | Year |
|---|---|
Lipidic cubic-phase leflunomide nanoparticles (cubosomes) as a potential tool for breast cancer management.
Topics: Administration, Cutaneous; Breast Neoplasms; Female; Humans; Leflunomide; Nanoparticles; Particle Si | 2022 |
Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle Checkpoints; C | 2020 |
Alpha-cyano-beta-hydroxy-beta-methyl-N-[4-(trifluoromethoxy)phenyl] propenamide: an inhibitor of the epidermal growth factor receptor tyrosine kinase with potent cytotoxic activity against breast cancer cells.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line; Cell Survival; Dru | 1998 |