leflunomide has been researched along with Brain Neoplasms in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shawver, LK | 1 |
| Schwartz, DP | 1 |
| Mann, E | 1 |
| Chen, H | 1 |
| Tsai, J | 1 |
| Chu, L | 1 |
| Taylorson, L | 1 |
| Longhi, M | 1 |
| Meredith, S | 1 |
| Germain, L | 1 |
| Jacobs, JS | 1 |
| Tang, C | 1 |
| Ullrich, A | 1 |
| Berens, ME | 1 |
| Hersh, E | 1 |
| McMahon, G | 1 |
| Hirth, KP | 1 |
| Powell, TJ | 1 |
1 other study available for leflunomide and Brain Neoplasms
| Article | Year |
|---|---|
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
Topics: 3T3 Cells; Animals; Brain Neoplasms; Cell Survival; Epidermal Growth Factor; Female; Glioma; Growth | 1997 |