Page last updated: 2024-10-30

leflunomide and Blood Poisoning

leflunomide has been researched along with Blood Poisoning in 3 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
"Wistar albino type rats were randomly divided into five groups: control, sham, leflunomide, sepsis, and sepsis + leflunomide."7.80Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis. ( Fadillioglu, E; Karaman, A; Ozturk, E; Samdancı, E; Surucu, M, 2014)
"To determine the prevalence of severe infections in patients with rheumatoid arthritis (RA) prescribed leflunomide in North Canterbury, New Zealand."7.74Leflunomide-associated infections in rheumatoid arthritis. ( Chapman, PT; Jenks, KA; O'Donnell, JL; Savage, RL; Stamp, LK, 2007)
"Wistar albino type rats were randomly divided into five groups: control, sham, leflunomide, sepsis, and sepsis + leflunomide."3.80Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis. ( Fadillioglu, E; Karaman, A; Ozturk, E; Samdancı, E; Surucu, M, 2014)
"To determine the prevalence of severe infections in patients with rheumatoid arthritis (RA) prescribed leflunomide in North Canterbury, New Zealand."3.74Leflunomide-associated infections in rheumatoid arthritis. ( Chapman, PT; Jenks, KA; O'Donnell, JL; Savage, RL; Stamp, LK, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozturk, E2
Surucu, M2
Karaman, A1
Samdancı, E1
Fadillioglu, E2
Demirbilek, S1
Begec, Z1
Kirimlioglu, H1
Ersoy, MO1
Jenks, KA1
Stamp, LK1
O'Donnell, JL1
Savage, RL1
Chapman, PT1

Other Studies

3 other studies available for leflunomide and Blood Poisoning

ArticleYear
Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis.
    The Journal of surgical research, 2014, Volume: 187, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Catalase; Cecum; Disease

2014
Does leflunomide attenuate the sepsis-induced acute lung injury?
    Pediatric surgery international, 2008, Volume: 24, Issue:8

    Topics: Acute Lung Injury; Adjuvants, Immunologic; Animals; Disease Models, Animal; Glutathione; Immunosuppr

2008
Leflunomide-associated infections in rheumatoid arthritis.
    The Journal of rheumatology, 2007, Volume: 34, Issue:11

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cellulitis; Female; Hospitalization; Human

2007