leflunomide has been researched along with Blood Clot in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with leflunomide seemed to be associated with a new toxicity, hemolysis, seen in four of the 27 patients so treated." | 5.35 | Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients. ( Davis, CL; de Boer, IH; Jefferson, JA; Kendrick, EA; Kowalewska, J; Leca, N; Muczynski, KA; Pichler, R, 2008) |
| "Treatment with leflunomide seemed to be associated with a new toxicity, hemolysis, seen in four of the 27 patients so treated." | 1.35 | Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients. ( Davis, CL; de Boer, IH; Jefferson, JA; Kendrick, EA; Kowalewska, J; Leca, N; Muczynski, KA; Pichler, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leca, N | 1 |
| Muczynski, KA | 1 |
| Jefferson, JA | 1 |
| de Boer, IH | 1 |
| Kowalewska, J | 1 |
| Kendrick, EA | 1 |
| Pichler, R | 1 |
| Davis, CL | 1 |
| Mannon, RB | 1 |
2 other studies available for leflunomide and Blood Clot
| Article | Year |
|---|---|
Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients.
Topics: Adult; Aged; Antiviral Agents; BK Virus; Dose-Response Relationship, Drug; Female; Graft Rejection; | 2008 |
Leflunomide therapy in kidney transplantation: ready for prime time?
Topics: Antiviral Agents; BK Virus; Dose-Response Relationship, Drug; Graft Rejection; Hemolysis; Humans; Im | 2008 |