leflunomide has been researched along with Bile Duct Obstruction, Extrahepatic in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with leflunomide markedly reduced serum transaminase activities as compared to BDL rats." | 1.33 | Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment. ( Fadillioglu, E; Iraz, M; Karadag, N; Karaman, A; Kirimlioglu, H; Tas, E, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karaman, A | 1 |
| Iraz, M | 1 |
| Kirimlioglu, H | 1 |
| Karadag, N | 1 |
| Tas, E | 1 |
| Fadillioglu, E | 1 |
1 other study available for leflunomide and Bile Duct Obstruction, Extrahepatic
| Article | Year |
|---|---|
Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment.
Topics: Analysis of Variance; Animals; Cholestasis, Extrahepatic; Female; Immunosuppressive Agents; Isoxazol | 2006 |