leflunomide has been researched along with Benign Neoplasms, Brain in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shawver, LK | 1 |
| Schwartz, DP | 1 |
| Mann, E | 1 |
| Chen, H | 1 |
| Tsai, J | 1 |
| Chu, L | 1 |
| Taylorson, L | 1 |
| Longhi, M | 1 |
| Meredith, S | 1 |
| Germain, L | 1 |
| Jacobs, JS | 1 |
| Tang, C | 1 |
| Ullrich, A | 1 |
| Berens, ME | 1 |
| Hersh, E | 1 |
| McMahon, G | 1 |
| Hirth, KP | 1 |
| Powell, TJ | 1 |
1 other study available for leflunomide and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
Topics: 3T3 Cells; Animals; Brain Neoplasms; Cell Survival; Epidermal Growth Factor; Female; Glioma; Growth | 1997 |