Page last updated: 2024-10-30

leflunomide and Anemia

leflunomide has been researched along with Anemia in 4 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia."7.74The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007)
"Rheumatoid arthritis is a chronic disease of the joints, which causes joint pain and disability."5.48Treatment with either leflunomide or adalimumab reduces anaemia in patients with rheumatoid arthritis. ( Colares, VLP; Fernandes, AMR; Fernandes, ES; Martins, MMRS; Mendes, SJF; Monteiro, CRAV; Muniz, TF; Pereira, DMS; Pereira, ICP; Silva, BLR; Sousa, NCF, 2018)
"To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia."3.74The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007)
"Rheumatoid arthritis is a chronic disease of the joints, which causes joint pain and disability."1.48Treatment with either leflunomide or adalimumab reduces anaemia in patients with rheumatoid arthritis. ( Colares, VLP; Fernandes, AMR; Fernandes, ES; Martins, MMRS; Mendes, SJF; Monteiro, CRAV; Muniz, TF; Pereira, DMS; Pereira, ICP; Silva, BLR; Sousa, NCF, 2018)
"The prednisone dose was reduced by a mean of 25% in these same 13 patients."1.31Experiences with leflunomide in solid organ transplantation. ( Brady, L; Chong, A; Huang, W; Jensik, S; Kottayil, A; Longstreth, J; Millis, M; Mital, D; Williams, JW, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pereira, ICP1
Sousa, NCF1
Pereira, DMS1
Mendes, SJF1
Muniz, TF1
Colares, VLP1
Silva, BLR1
Monteiro, CRAV1
Martins, MMRS1
Fernandes, AMR1
Fernandes, ES1
Wang, H1
Sun, L1
Tan, W1
McEwen, J1
Purcell, PM1
Hill, RL1
Calcino, LJ1
Riley, CG1
Williams, JW1
Mital, D1
Chong, A1
Kottayil, A1
Millis, M1
Longstreth, J1
Huang, W1
Brady, L1
Jensik, S1

Other Studies

4 other studies available for leflunomide and Anemia

ArticleYear
Treatment with either leflunomide or adalimumab reduces anaemia in patients with rheumatoid arthritis.
    Anais da Academia Brasileira de Ciencias, 2018, Volume: 90, Issue:2 suppl 1

    Topics: Adalimumab; Adult; Anemia; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Isoxazoles;

2018
Clinical features of children with pulmonary microscopic polyangiitis: report of 9 cases.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adolescent; Anemia; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Child; Child,

2015
The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An

2007
Experiences with leflunomide in solid organ transplantation.
    Transplantation, 2002, Feb-15, Volume: 73, Issue:3

    Topics: Anemia; Calcineurin Inhibitors; Creatinine; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Tra

2002