leflunomide has been researched along with Alveolitis, Extrinsic Allergic in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Alveolitis, Extrinsic Allergic: A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide treatment was associated with significant gastrointestinal and other adverse effects leading 40% of patients to discontinue therapy." | 1.56 | Use of leflunomide in patients with chronic hypersensitivity pneumonitis. ( Culver, DA; Li, M; Noh, S; Pande, A; Sahoo, D; Wang, X; Yadav, R, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Noh, S | 1 |
| Yadav, R | 1 |
| Li, M | 1 |
| Wang, X | 1 |
| Sahoo, D | 1 |
| Culver, DA | 1 |
| Pande, A | 1 |
| Wong, SP | 1 |
| Chu, CM | 1 |
| Kan, CH | 1 |
| Tsui, HS | 1 |
| Ng, WL | 1 |
| Sugiyama, Y | 1 |
| Chida, K | 1 |
| Ogura, T | 1 |
| Yamaguchi, T | 1 |
| Miyazaki, K | 1 |
| Martin, N | 1 |
| Innes, JA | 1 |
| Lambert, CM | 1 |
| Turnbull, CM | 1 |
| Wallace, WA | 1 |
4 other studies available for leflunomide and Alveolitis, Extrinsic Allergic
| Article | Year |
|---|---|
Use of leflunomide in patients with chronic hypersensitivity pneumonitis.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Carbon Monoxide; Chronic Disease; Female; Humans; Immun | 2020 |
Successful treatment of leflunomide-induced acute pneumonitis with cholestyramine wash-out therapy.
Topics: Adult; Alveolitis, Extrinsic Allergic; Anion Exchange Resins; Antirheumatic Agents; Arthritis, Rheum | 2009 |
[Diagnosis of and therapy for diffuse lung diseases (discussion)].
Topics: Alveolitis, Extrinsic Allergic; Biomarkers; Bronchiolitis; Gefitinib; Humans; Isoxazoles; Leflunomid | 2006 |
Hypersensitivity pneumonitis associated with leflunomide therapy.
Topics: Aged; Alveolitis, Extrinsic Allergic; Arthritis, Rheumatoid; Biopsy; Humans; Immunosuppressive Agent | 2007 |