leflunomide has been researched along with Alopecia Circumscripta in 9 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report the case of a 43-year-old man with psoriasis and psoriatic arthritis who developed AA during his treatment with adalimumab and leflunomide." | 8.88 | Alopecia areata during treatment of psoriasis with adalimumab and leflunomide: a case and review of the literature. ( Daudén, E; Gallo, E; García-Diez, A; Navarro, R; Santiago Sánchez-Mateos, D, 2012) |
| "Leflunomide is a disease-modifying anti-rheumatic drug (DMARD) used in the management of rheumatoid arthritis (RA) and psoriatic arthritis." | 7.91 | Reversible alopecia areata: a little known side effect of leflunomide. ( Cusnir, I; Hall, J; Koller, G; Ye, C, 2019) |
| "Rheumatoid arthritis is a chronic, highly disabling autoimmune disease that requires aggressive pharmacological treatment using immunomodulatory drugs grouped under the name of Disease-Modifying Anti-rheumatic Drugs (DMARDs)." | 6.52 | [Alopecia areata secondary to the use of leflunomide in patients with rheumatoid arthritis: a case report and literature review]. ( Molina Molina, MI; Pinochet Paiva, CM; Quezada Morales, JI, 2015) |
| " We report the case of a 43-year-old man with psoriasis and psoriatic arthritis who developed AA during his treatment with adalimumab and leflunomide." | 4.88 | Alopecia areata during treatment of psoriasis with adalimumab and leflunomide: a case and review of the literature. ( Daudén, E; Gallo, E; García-Diez, A; Navarro, R; Santiago Sánchez-Mateos, D, 2012) |
| "Leflunomide is a disease-modifying anti-rheumatic drug (DMARD) used in the management of rheumatoid arthritis (RA) and psoriatic arthritis." | 3.91 | Reversible alopecia areata: a little known side effect of leflunomide. ( Cusnir, I; Hall, J; Koller, G; Ye, C, 2019) |
| "Alopecia areata is the third most common cause of dermatology consultations in children but the treatment of paediatric alopecia areata remains challenging." | 2.72 | Therapeutic management in paediatric alopecia areata: A systematic review. ( Kołodziejak, M; Olszewska, M; Rakowska, A; Rudnicka, L; Sikora, M; Stochmal, A; Waśkiel-Burnat, A, 2021) |
| "Rheumatoid arthritis is a chronic, highly disabling autoimmune disease that requires aggressive pharmacological treatment using immunomodulatory drugs grouped under the name of Disease-Modifying Anti-rheumatic Drugs (DMARDs)." | 2.52 | [Alopecia areata secondary to the use of leflunomide in patients with rheumatoid arthritis: a case report and literature review]. ( Molina Molina, MI; Pinochet Paiva, CM; Quezada Morales, JI, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Mathachan, SR | 1 |
| Sardana, K | 3 |
| Khurana, A | 1 |
| Waśkiel-Burnat, A | 1 |
| Kołodziejak, M | 1 |
| Sikora, M | 1 |
| Stochmal, A | 1 |
| Rakowska, A | 1 |
| Olszewska, M | 1 |
| Rudnicka, L | 1 |
| Gupta, A | 2 |
| Gautam, RK | 1 |
| Koller, G | 2 |
| Cusnir, I | 1 |
| Hall, J | 2 |
| Ye, C | 2 |
| Gupta, PK | 1 |
| Molina Molina, MI | 1 |
| Pinochet Paiva, CM | 1 |
| Quezada Morales, JI | 1 |
| Navarro, R | 1 |
| Daudén, E | 1 |
| Gallo, E | 1 |
| Santiago Sánchez-Mateos, D | 1 |
| García-Diez, A | 1 |
| Gottenberg, JE | 1 |
| Venancie, PY | 1 |
| Mariette, X | 1 |
3 reviews available for leflunomide and Alopecia Circumscripta
| Article | Year |
|---|---|
Therapeutic management in paediatric alopecia areata: A systematic review.
Topics: Adolescent; Alopecia; Alopecia Areata; Child; Humans; Janus Kinase Inhibitors; Leflunomide; Minoxidi | 2021 |
[Alopecia areata secondary to the use of leflunomide in patients with rheumatoid arthritis: a case report and literature review].
Topics: Adult; Alopecia Areata; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Isoxazoles; Lef | 2015 |
Alopecia areata during treatment of psoriasis with adalimumab and leflunomide: a case and review of the literature.
Topics: Adalimumab; Adult; Alopecia Areata; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Hum | 2012 |
6 other studies available for leflunomide and Alopecia Circumscripta
| Article | Year |
|---|---|
A study examining the combination of methotrexate and leflunomide with topical anthralin in pediatric alopecia areata-a possible steroid-free regimen with diverse mechanistic actions.
Topics: Administration, Topical; Alopecia Areata; Anthralin; Child; Humans; Leflunomide; Methotrexate | 2022 |
Recalcitrant alopecia areata responsive to leflunomide and anthralin-Potentially undiscovered JAK/STAT inhibitors?
Topics: Administration, Topical; Adolescent; Alopecia Areata; Anthralin; Dermatologic Agents; Hair; Humans; | 2018 |
Reversible alopecia areata: a little known side effect of leflunomide.
Topics: Adult; Alopecia Areata; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Leflunomide | 2019 |
Leflunomide: an unlikely trigger and mechanistically a beneficial drug for alopecia areata.
Topics: Alopecia Areata; Drug-Related Side Effects and Adverse Reactions; Humans; Isoxazoles; Leflunomide | 2019 |
Response: Leflunomide: potential treatment and cause of alopecia areata.
Topics: Alopecia Areata; Humans; Isoxazoles; Leflunomide | 2019 |
Alopecia areata in a patient with rheumatoid arthritis treated with leflunomide.
Topics: Alopecia Areata; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Iso | 2002 |