leflunomide has been researched along with Allergic Alveolitis, Extrinsic in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide treatment was associated with significant gastrointestinal and other adverse effects leading 40% of patients to discontinue therapy." | 1.56 | Use of leflunomide in patients with chronic hypersensitivity pneumonitis. ( Culver, DA; Li, M; Noh, S; Pande, A; Sahoo, D; Wang, X; Yadav, R, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Noh, S | 1 |
| Yadav, R | 1 |
| Li, M | 1 |
| Wang, X | 1 |
| Sahoo, D | 1 |
| Culver, DA | 1 |
| Pande, A | 1 |
| Wong, SP | 1 |
| Chu, CM | 1 |
| Kan, CH | 1 |
| Tsui, HS | 1 |
| Ng, WL | 1 |
| Sugiyama, Y | 1 |
| Chida, K | 1 |
| Ogura, T | 1 |
| Yamaguchi, T | 1 |
| Miyazaki, K | 1 |
| Martin, N | 1 |
| Innes, JA | 1 |
| Lambert, CM | 1 |
| Turnbull, CM | 1 |
| Wallace, WA | 1 |
4 other studies available for leflunomide and Allergic Alveolitis, Extrinsic
| Article | Year |
|---|---|
Use of leflunomide in patients with chronic hypersensitivity pneumonitis.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Carbon Monoxide; Chronic Disease; Female; Humans; Immun | 2020 |
Successful treatment of leflunomide-induced acute pneumonitis with cholestyramine wash-out therapy.
Topics: Adult; Alveolitis, Extrinsic Allergic; Anion Exchange Resins; Antirheumatic Agents; Arthritis, Rheum | 2009 |
[Diagnosis of and therapy for diffuse lung diseases (discussion)].
Topics: Alveolitis, Extrinsic Allergic; Biomarkers; Bronchiolitis; Gefitinib; Humans; Isoxazoles; Leflunomid | 2006 |
Hypersensitivity pneumonitis associated with leflunomide therapy.
Topics: Aged; Alveolitis, Extrinsic Allergic; Arthritis, Rheumatoid; Biopsy; Humans; Immunosuppressive Agent | 2007 |