leflunomide has been researched along with Acute Rheumatic Fever in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gremese, E | 1 |
| Alivernini, S | 1 |
| Tolusso, B | 1 |
| Zeidler, MP | 1 |
| Ferraccioli, G | 1 |
| Banas, T | 1 |
| Hadyla-Banas, I | 1 |
| Pityński, K | 1 |
| Bereza, K | 1 |
| Migdal, M | 1 |
| Batko, B | 1 |
1 review available for leflunomide and Acute Rheumatic Fever
| Article | Year |
|---|---|
JAK inhibition by methotrexate (and csDMARDs) may explain clinical efficacy as monotherapy and combination therapy.
Topics: Animals; Arthritis, Psoriatic; Drug Therapy, Combination; Humans; Janus Kinase 1; Janus Kinase 2; Ja | 2019 |
1 other study available for leflunomide and Acute Rheumatic Fever
| Article | Year |
|---|---|
Use of contraception by women treated with leflunomide due to rheumatic arthritis.
Topics: Adult; Antirheumatic Agents; Case-Control Studies; Contraception; Contraception Behavior; Female; Hu | 2014 |