leflunomide has been researched along with Acute Necrotizing Pancreatitis in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide pretreatment significantly ameliorated pancreatic hemorrhage, edema, and neutrophil infiltration and decreased histopathological score compared with the untreated severe necrotizing pancreatitis group (pathological score [mean +/- SEM]: 6." | 1.36 | Leflunomide: is a new oral agent in treatment of acute pancreatitis? ( Kaptanoglu, B; Kutluana, U; Nart, D; Oruc, N; Ozutemiz, O; Yonetci, N, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kutluana, U | 1 |
| Oruc, N | 1 |
| Nart, D | 1 |
| Kaptanoglu, B | 1 |
| Yonetci, N | 1 |
| Ozutemiz, O | 1 |
1 other study available for leflunomide and Acute Necrotizing Pancreatitis
| Article | Year |
|---|---|
Leflunomide: is a new oral agent in treatment of acute pancreatitis?
Topics: Administration, Oral; Amylases; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Isoxazole | 2010 |