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leflunomide and Acute Necrotizing Pancreatitis

leflunomide has been researched along with Acute Necrotizing Pancreatitis in 1 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
"Leflunomide pretreatment significantly ameliorated pancreatic hemorrhage, edema, and neutrophil infiltration and decreased histopathological score compared with the untreated severe necrotizing pancreatitis group (pathological score [mean +/- SEM]: 6."1.36Leflunomide: is a new oral agent in treatment of acute pancreatitis? ( Kaptanoglu, B; Kutluana, U; Nart, D; Oruc, N; Ozutemiz, O; Yonetci, N, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kutluana, U1
Oruc, N1
Nart, D1
Kaptanoglu, B1
Yonetci, N1
Ozutemiz, O1

Other Studies

1 other study available for leflunomide and Acute Necrotizing Pancreatitis

ArticleYear
Leflunomide: is a new oral agent in treatment of acute pancreatitis?
    Pancreas, 2010, Volume: 39, Issue:2

    Topics: Administration, Oral; Amylases; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Isoxazole

2010