leflunomide has been researched along with Acute Lung Injury in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yilmaz, MZ | 1 |
| Torun, AC | 1 |
| Guzel, A | 2 |
| Murat, N | 1 |
| Okuyucu, A | 1 |
| Yilmaz, N | 1 |
| Gacar, A | 1 |
| Guvenc, T | 1 |
| Ozturk, E | 1 |
| Demirbilek, S | 1 |
| Begec, Z | 1 |
| Surucu, M | 1 |
| Fadillioglu, E | 1 |
| Kirimlioglu, H | 1 |
| Ersoy, MO | 1 |
2 other studies available for leflunomide and Acute Lung Injury
| Article | Year |
|---|---|
Ameliorative effect of Leflunomide on lung injury following an aspiration.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Isoxazoles; Leflu | 2015 |
Does leflunomide attenuate the sepsis-induced acute lung injury?
Topics: Acute Lung Injury; Adjuvants, Immunologic; Animals; Disease Models, Animal; Glutathione; Immunosuppr | 2008 |