leflunomide has been researched along with Acquired Hyperostosis Syndrome in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Acquired Hyperostosis Syndrome: Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cornillier, H | 1 |
| Kervarrec, T | 1 |
| Tabareau-Delalande, F | 1 |
| Mammou, S | 1 |
| Jonville Bera, AP | 1 |
| Machet, L | 1 |
| Zhao, Z | 1 |
| Li, Y | 2 |
| Zhao, H | 1 |
| Li, H | 1 |
1 review available for leflunomide and Acquired Hyperostosis Syndrome
| Article | Year |
|---|---|
Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with review of the relevant published work.
Topics: Acquired Hyperostosis Syndrome; Adult; Dermatologic Agents; Diagnosis, Differential; Female; Hand De | 2011 |
1 other study available for leflunomide and Acquired Hyperostosis Syndrome
| Article | Year |
|---|---|
Interstitial granulomatous dermatitis occurring in a patient with SAPHO syndrome one month after starting leflunomide, and subsequently disappearing with ustekinumab.
Topics: Acquired Hyperostosis Syndrome; Adult; Dermatitis; Dermatologic Agents; Drug Eruptions; Female; Gran | 2016 |