ledipasvir and Glomerulonephritis--Membranous

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various.. We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free.. We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.

Topics: Aged; Anti-Inflammatory Agents; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Fluorenes; Glomerulonephritis, Membranous; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Prednisolone; Prognosis; Sofosbuvir