lead-radioisotopes and Necrosis

lead-radioisotopes has been researched along with Necrosis* in 1 studies

Other Studies

1 other study(ies) available for lead-radioisotopes and Necrosis

Article	Year
Monte Carlo simulations of dose distributions with necrotic tumor targeted radioimmunotherapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 90 Radio-resistant hypoxic tumor cells are significant contributors to the locoregional recurrences and distant metastases that mark failure of radiotherapy. Due to restricted tissue oxygenation, chronically hypoxic tumor cells frequently become necrotic and thus there is often an association between chronically hypoxic and necrotic tumor regions. This simulation study is the first in a series to determine the feasibility of hypoxic cell killing after first targeting adjacent areas of necrosis with either an α- or β-emitting radioimmunoconjugate. Topics: Absorption, Radiation; Computer Simulation; Humans; Lead Radioisotopes; Models, Statistical; Monte Carlo Method; Necrosis; Neoplasms; Radioimmunotherapy; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted	2014

Article

Year

Monte Carlo simulations of dose distributions with necrotic tumor targeted radioimmunotherapy.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 90

Radio-resistant hypoxic tumor cells are significant contributors to the locoregional recurrences and distant metastases that mark failure of radiotherapy. Due to restricted tissue oxygenation, chronically hypoxic tumor cells frequently become necrotic and thus there is often an association between chronically hypoxic and necrotic tumor regions. This simulation study is the first in a series to determine the feasibility of hypoxic cell killing after first targeting adjacent areas of necrosis with either an α- or β-emitting radioimmunoconjugate.

Topics: Absorption, Radiation; Computer Simulation; Humans; Lead Radioisotopes; Models, Statistical; Monte Carlo Method; Necrosis; Neoplasms; Radioimmunotherapy; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted

2014