lb-100 and Lung-Neoplasms

lb-100 has been researched along with Lung-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for lb-100 and Lung-Neoplasms

Article	Year
Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer. Molecular cancer therapeutics, 2021, Volume: 20, Issue:10 Protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of apoptosis, proliferation, and DNA-damage response, is overexpressed in many cancers, including small cell lung cancer (SCLC). Here we report that LB100, a small molecule inhibitor of PP2A, when combined with platinum-based chemotherapy, synergistically elicited an antitumor response both Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Piperazines; Protein Phosphatase 2; Small Cell Lung Carcinoma; Tumor Cells, Cultured	2021

Article

Year

Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.

Molecular cancer therapeutics, 2021, Volume: 20, Issue:10

Protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of apoptosis, proliferation, and DNA-damage response, is overexpressed in many cancers, including small cell lung cancer (SCLC). Here we report that LB100, a small molecule inhibitor of PP2A, when combined with platinum-based chemotherapy, synergistically elicited an antitumor response both

Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Piperazines; Protein Phosphatase 2; Small Cell Lung Carcinoma; Tumor Cells, Cultured

2021