Page last updated: 2024-08-25

lazabemide and Idiopathic Parkinson Disease

lazabemide has been researched along with Idiopathic Parkinson Disease in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (50.00)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almos, T; Edmondson, DE; Massari, ME; Rojas, RJ; Scott, R1
Legoabe, LJ; Petzer, A; Petzer, JP; Qhobosheane, MA1
Ji, F; Jiang, R; Su, Z; Xue, R; Zhou, Y; Zhu, X; Zhuo, C1
Hoon, M; Petzer, A; Petzer, JP; Viljoen, F1
LeWitt, PA1
Counsell, CE; Ives, N; Macleod, AD; Stowe, R1
Alexoff, D; Fowler, JS; Logan, J; MacGregor, RR; Pappas, N; Schlyer, DJ; Shea, C; Volkow, ND; Wang, GJ; Wolf, AP1
Ogawa, N1
Da Prada, M1

Reviews

5 review(s) available for lazabemide and Idiopathic Parkinson Disease

ArticleYear
Comparison for Efficacy and Tolerability among Ten Drugs for Treatment of Parkinson's Disease: A Network Meta-Analysis.
    Scientific reports, 2017, 04-04, Volume: 8

    Topics: Bromocriptine; Cluster Analysis; Dopamine Agonists; Drug Therapy, Combination; Humans; Indoles; Levodopa; Network Meta-Analysis; Parkinson Disease; Picolinic Acids; Pramipexole; Selegiline; Tetrahydronaphthalenes; Thiophenes

2017
Clinical trials of neuroprotection for Parkinson's disease.
    Neurology, 2004, Oct-12, Volume: 63, Issue:7 Suppl 2

    Topics: Antiparkinson Agents; Clinical Trials as Topic; Creatine; Dopamine Agonists; Double-Blind Method; Humans; Indans; Minocycline; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Multicenter Studies as Topic; Nerve Tissue Proteins; Neuroprotective Agents; Oxepins; Parkinson Disease; Picolinic Acids; Randomized Controlled Trials as Topic; Riluzole; Selegiline; Ubiquinone

2004
Monoamine oxidase B inhibitors for early Parkinson's disease.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Antiparkinson Agents; Dopamine Agonists; Humans; Levodopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Randomized Controlled Trials as Topic; Selegiline

2005
[New anti-parkinsonian drugs].
    No to shinkei = Brain and nerve, 1991, Volume: 43, Issue:8

    Topics: Antiparkinson Agents; Bromocriptine; Humans; Lisuride; Parkinson Disease; Pergolide; Picolinic Acids; Selegiline

1991
New approaches to the treatment of age-related brain disorders.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1991, Volume: 18, Issue:3 Suppl

    Topics: Aging; Alzheimer Disease; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Enzyme Inhibitors; Humans; Levodopa; Monoamine Oxidase Inhibitors; Nitrophenols; Parkinson Disease; Picolinic Acids; Tolcapone

1991

Trials

3 trial(s) available for lazabemide and Idiopathic Parkinson Disease

ArticleYear
A controlled trial of lazabemide (Ro 19-6327) in levodopa-treated Parkinson's disease. Parkinson Study Group.
    Archives of neurology, 1994, Volume: 51, Issue:4

    Topics: Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids

1994
A controlled trial of lazabemide (RO19-6327) in untreated Parkinson's disease. Parkinson Study Group.
    Annals of neurology, 1993, Volume: 33, Issue:4

    Topics: Activities of Daily Living; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Severity of Illness Index

1993
Effect of lazabemide on the progression of disability in early Parkinson's disease. The Parkinson Study Group.
    Annals of neurology, 1996, Volume: 40, Issue:1

    Topics: Aged; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Treatment Outcome

1996

Other Studies

4 other study(ies) available for lazabemide and Idiopathic Parkinson Disease

ArticleYear
Reversible and irreversible small molecule inhibitors of monoamine oxidase B (MAO-B) investigated by biophysical techniques.
    Bioorganic & medicinal chemistry, 2015, Feb-15, Volume: 23, Issue:4

    Topics: Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Small Molecule Libraries; Thermodynamics

2015
Synthesis and evaluation of 2-substituted 4(3H)-quinazolinone thioether derivatives as monoamine oxidase inhibitors.
    Bioorganic & medicinal chemistry, 2018, 11-01, Volume: 26, Issue:20

    Topics: Chemistry Techniques, Synthetic; Humans; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Quinazolinones; Structure-Activity Relationship

2018
The Design and Evaluation of an l-Dopa-Lazabemide Prodrug for the Treatment of Parkinson's Disease.
    Molecules (Basel, Switzerland), 2017, Nov-27, Volume: 22, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Availability; Carbidopa; Corpus Striatum; Dopamine; Drug Combinations; HeLa Cells; Humans; Levodopa; Male; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Permeability; Picolinic Acids; Prodrugs; Solubility; Structure-Activity Relationship

2017
Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease: the degree and reversibility of human brain MAO B inhibition by Ro 19 6327.
    Neurology, 1993, Volume: 43, Issue:10

    Topics: Aged; Antiparkinson Agents; Brain; Carbon Radioisotopes; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Monoamine Oxidase; Parkinson Disease; Picolinic Acids; Reference Values; Selegiline; Tomography, Emission-Computed

1993