latrunculin-a has been researched along with Fibrosarcoma* in 1 studies
1 other study(ies) available for latrunculin-a and Fibrosarcoma
| Article | Year |
|---|---|
Actin stress fiber retraction and aggresome formation is a common cellular response to actin toxins.
F-actin-stabilizing drugs induce actin aggresome formation. In this study, we found that an actin-depolymerizing drug, latrunculin A (LatA), induced actin aggresomes. Actin stress fibers were retracted and disappeared in minutes, but a large aggresome formed in consequence of LatA treatment. Because cytochalasin D and mycalolide also induced aggresome formation, these results suggest that actin aggresome formation is a common cellular response to actin toxins. Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Cytochalasin D; Fibroblasts; Fibrosarcoma; Humans; Marine Toxins; Microscopy, Fluorescence; Microscopy, Video; Protein Folding; Rats; Stress Fibers; Stress, Physiological; Thiazolidines | 2011 |