Page last updated: 2024-09-05

latrepirdine and Amyotrophic Lateral Sclerosis

latrepirdine has been researched along with Amyotrophic Lateral Sclerosis in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Hawker, DD; Jansen Labby, K; Mataka, JJ; Silverman, RB; Trippier, PC1
Bachurin, SO; Buchman, VL; Chaprov, K; Deykin, AV; Funikov, S; Ivanova, TA; Kukharsky, MS; Lysikova, EA; Ninkina, N; Rezvykh, A; Yu Aksinenko, A1
Coughlan, KS; Hogg, MC; Mitchem, MR; Prehn, JH1
Akiyama, H; Arai, T; Bachurin, SO; Buchman, VL; Goedert, M; Hasegawa, M; Kametani, F; Ninkina, N; Nonaka, T; Yamashita, M1
Afanasieva, MA; Alentov, II; Bachurin, SO; Buchman, VL; Khritankova, I; Ninkina, NN; Peters, O; Shelkovnikova, TA; Tarasova, TV; Ustyugov, AA1
Burket, A; Drawbridge, J; Estill, SJ; Huntington, P; Knobbe, W; McDaniel, L; McKnight, SL; Morlock, L; Naidoo, J; Pieper, AA; Ready, JM; Starwalt, R; Tesla, R; Tran, S; Williams, NS; Wolf, HP; Xu, P1

Reviews

1 review(s) available for latrepirdine and Amyotrophic Lateral Sclerosis

ArticleYear
Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers.
    Journal of medicinal chemistry, 2013, Apr-25, Volume: 56, Issue:8

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Calcium Channels; Drug Combinations; Drug Design; Humans; Huntington Disease; Neurodegenerative Diseases; Nitric Oxide Synthase Type I; Oxidative Stress; Parkinson Disease; Protein Folding; Protein Structure, Quaternary; Proteostasis Deficiencies; Receptors, N-Methyl-D-Aspartate

2013

Other Studies

5 other study(ies) available for latrepirdine and Amyotrophic Lateral Sclerosis

ArticleYear
A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice.
    CNS neuroscience & therapeutics, 2021, Volume: 27, Issue:7

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Progression; Gait; Humans; Indoles; Mice; Mice, Transgenic; RNA-Binding Protein FUS

2021
"Preconditioning" with latrepirdine, an adenosine 5'-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice.
    Neurobiology of aging, 2015, Volume: 36, Issue:2

    Topics: AMP-Activated Protein Kinases; Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Disease Progression; Energy Metabolism; Enzyme Activation; Female; Indoles; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Mutation; Risk; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1

2015
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.
    FEBS letters, 2009, Jul-21, Volume: 583, Issue:14

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Cell Line; Dementia; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Inclusion Bodies; Indoles; Methylene Blue

2009
Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice.
    Neurotoxicity research, 2012, Volume: 22, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; gamma-Synuclein; Indoles; Male; Mice; Mice, Transgenic; Motor Neurons; Neuroprotective Agents; Rotarod Performance Test; Spinal Cord

2012
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-16, Volume: 109, Issue:42

    Topics: Amyotrophic Lateral Sclerosis; Animals; Carbazoles; Indoles; Mice; Motor Activity; Motor Neurons; Neuroprotective Agents; Polymerase Chain Reaction; Rotarod Performance Test; Spinal Cord

2012