Page last updated: 2024-09-05

latrepirdine and Akinetic-Rigid Variant of Huntington Disease

latrepirdine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (11.11)	29.6817
2010's	8 (88.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hawker, DD; Jansen Labby, K; Mataka, JJ; Silverman, RB; Trippier, PC	1
Cano-Cuenca, N; Jordán, J; Solís-García del Pozo, JE	1
Bates, KA; Bharadwaj, PR; Gandy, S; Groth, D; Martins, RN; Perry, G; Porter, T; Steele, JW; Teimouri, E; Verdile, G	1
Sabbagh, MN; Shill, HA	1
Corey-Bloom, J; Deuel, LM; Dorsey, ER; Factor, S; Feigin, A; Geschwind, MD; Hodgeman, K; Kayson, E; Kieburtz, K; McDermott, MP; Noonberg, S; Pourfar, M; Rabinowitz, K; Ravina, B; Sanchez-Ramos, J; Seely, L; Voss, TS; Walker, F	1
Gao, M; Hutchins, GD; Wang, M; Zheng, QH	1
Bezprozvanny, I	1

Reviews

4 review(s) available for latrepirdine and Akinetic-Rigid Variant of Huntington Disease

Article	Year
Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers. Journal of medicinal chemistry, 2013, Apr-25, Volume: 56, Issue:8 Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Calcium Channels; Drug Combinations; Drug Design; Humans; Huntington Disease; Neurodegenerative Diseases; Nitric Oxide Synthase Type I; Oxidative Stress; Parkinson Disease; Protein Folding; Protein Structure, Quaternary; Proteostasis Deficiencies; Receptors, N-Methyl-D-Aspartate	2013
Evidence for the efficacy of latrepirdine (Dimebon) treatment for improvement of cognitive function: a meta-analysis. Journal of Alzheimer's disease : JAD, 2014, Volume: 38, Issue:1 Topics: Alzheimer Disease; Antipsychotic Agents; Cognition Disorders; Humans; Huntington Disease; Indoles; MEDLINE; Neuropsychological Tests; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Schizophrenia	2014
Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Translational psychiatry, 2013, Dec-03, Volume: 3 Topics: Alzheimer Disease; Animals; Cognition; Humans; Huntington Disease; Indoles; Neurodegenerative Diseases; Neuroprotective Agents; Nootropic Agents	2013
Latrepirdine, a potential novel treatment for Alzheimer's disease and Huntington's chorea. Current opinion in investigational drugs (London, England : 2000), 2010, Volume: 11, Issue:1 Topics: Alzheimer Disease; Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Humans; Huntington Disease; Indoles; Nootropic Agents; Patents as Topic	2010

Trials

3 trial(s) available for latrepirdine and Akinetic-Rigid Variant of Huntington Disease

Article	Year
A randomized, placebo-controlled trial of latrepirdine in Huntington disease. Archives of neurology, 2010, Volume: 67, Issue:2 Topics: Adult; Aged; Antipsychotic Agents; Cognition; Double-Blind Method; Electrocardiography; Female; Humans; Huntington Disease; Indoles; Male; Mental Status Schedule; Middle Aged; Motor Activity; Neuropsychological Tests; Retrospective Studies; Time Factors; Treatment Outcome	2010
A randomized, double-blind, placebo-controlled study of latrepirdine in patients with mild to moderate Huntington disease. JAMA neurology, 2013, Volume: 70, Issue:1 Topics: Australia; Comorbidity; Double-Blind Method; Female; Humans; Huntington Disease; Indoles; Male; Middle Aged; North America; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Treatment Outcome	2013
Molecule of the Month. Dimebolin hydrochloride. Drug news & perspectives, 2007, Volume: 20, Issue:7 Topics: Alzheimer Disease; Double-Blind Method; Humans; Huntington Disease; Indoles	2007

Other Studies

2 other study(ies) available for latrepirdine and Akinetic-Rigid Variant of Huntington Disease

Article	Year
[(11)C]Dimebon, radiosynthesis and lipophilicity of a new potential PET agent for imaging of Alzheimer's disease and Huntington's disease. Bioorganic & medicinal chemistry letters, 2010, Apr-15, Volume: 20, Issue:8 Topics: Alzheimer Disease; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Humans; Huntington Disease; Indoles; Positron-Emission Tomography	2010
The rise and fall of Dimebon. Drug news & perspectives, 2010, Volume: 23, Issue:8 Topics: Alzheimer Disease; Animals; Controlled Clinical Trials as Topic; Humans; Huntington Disease; Indoles; Product Recalls and Withdrawals; Receptors, Histamine H1; Receptors, Serotonin; Russia; Treatment Failure	2010