latanoprost and Hyphema

A 74 year-old woman present with blurry vision of 12 hour duration in her right eye, and with no other symptoms. Biomicroscopic examination revealed a 3 mm hyphaema in her right eye and multiple nodular structures in the pupillary margin of both eyes.. Iris tufts are vascular anomalies unrelated to ischaemia that must be included in the differential diagnosis of spontaneous hyphaema.

Topics: Administration, Topical; Aged; Brimonidine Tartrate; Cyclopentolate; Dexamethasone; Diabetes Mellitus, Type 2; Female; Glaucoma, Open-Angle; Hamartoma; Humans; Hyphema; Iris Diseases; Latanoprost; Microscopy, Acoustic; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Vision Disorders

To describe an unusual hemorrhagic complication associated with pupillary dilation in a patient with exfoliation glaucoma taking anticoagulation therapy.. A 78-year-old woman with bilateral exfoliation glaucoma who was receiving warfarin, 2 mg daily, for systemic anticoagulation developed acute visual loss in the right eye several hours after pupillary dilation.. Examination disclosed bilateral advanced exfoliation glaucoma, localized vascularized iridolenticular adhesions in the right eye, and a 4-mm layered hyphema in the right eye.. Patients with exfoliation glaucoma and vascularized posterior synechiae who are receiving anticoagulation therapy are at increased risk for visually significant spontaneous hyphema after pupillary dilation.

Topics: Aged; Anticoagulants; Atrial Fibrillation; Carbachol; Cerebrovascular Disorders; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Hyphema; Latanoprost; Propranolol; Prostaglandins F, Synthetic; Pupil; Warfarin