lasiokaurin and Neoplasms

lasiokaurin has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for lasiokaurin and Neoplasms

Article	Year
Four new ent-kauranoids from Isodon rubescens var. lushanensis and data reassignment of dayecrystal B. Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:1 Four new 7, 20-epoxy-ent-kauranoids, rubluanins A-D (1-4) and eleven known ones, were isolated from Isodon rubescens var. lushanensis, and their structures were elucidated by spectroscopic analysis. Compounds 2-14 were evaluated for their cytotoxicity in several human tumor cell lines (U937, Jurkat, HL-60, K562, SGC790, and HepG2). Among the compounds, lasiokaurin (13) showed significant cytotoxic activity of 0.62 microM (IC(50)) in U937 cells. Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Diterpenes; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; Humans; Isodon; Models, Molecular; Molecular Structure; Neoplasms	2010

Article

Year

Four new ent-kauranoids from Isodon rubescens var. lushanensis and data reassignment of dayecrystal B.

Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:1

Four new 7, 20-epoxy-ent-kauranoids, rubluanins A-D (1-4) and eleven known ones, were isolated from Isodon rubescens var. lushanensis, and their structures were elucidated by spectroscopic analysis. Compounds 2-14 were evaluated for their cytotoxicity in several human tumor cell lines (U937, Jurkat, HL-60, K562, SGC790, and HepG2). Among the compounds, lasiokaurin (13) showed significant cytotoxic activity of 0.62 microM (IC(50)) in U937 cells.

Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Diterpenes; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; Humans; Isodon; Models, Molecular; Molecular Structure; Neoplasms

2010