lapachol has been researched along with Stomach Ulcer in 2 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " isabelii has been shown to display a gastroprotective effect in animal models of induced gastric ulcers while the quinone lapachol shows several biological effects associated with the use of the crude drug." | 3.78 | Potential gastroprotective effect of novel cyperenoic acid/quinone derivatives in human cell cultures. ( Carrión, IB; Pertino, MW; Schmeda-Hirschmann, G; Theoduloz, C; Valenzuela, D, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pertino, MW | 2 |
| Theoduloz, C | 2 |
| Palenzuela, JA | 1 |
| Afonso, Mdel M | 1 |
| Yesilada, E | 1 |
| Monsalve, F | 1 |
| González, P | 1 |
| Droguett, D | 1 |
| Schmeda-Hirschmann, G | 2 |
| Carrión, IB | 1 |
| Valenzuela, D | 1 |
2 other studies available for lapachol and Stomach Ulcer
| Article | Year |
|---|---|
Synthesis and pharmacological activity of diterpenylnaphthoquinone derivatives.
Topics: Animals; Anti-Ulcer Agents; Cell Line, Tumor; Diterpene Alkaloids; Diterpenes; Gastric Mucosa; Human | 2011 |
Potential gastroprotective effect of novel cyperenoic acid/quinone derivatives in human cell cultures.
Topics: Anti-Ulcer Agents; Cells, Cultured; Epithelial Cells; Fibroblasts; Gastric Mucosa; Humans; Jatropha; | 2012 |