lapachol has been researched along with Melanoma in 2 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lapachol was not detected in the stembark extract." | 1.29 | Activity of extracts of Kigelia pinnata against melanoma and renal carcinoma cell lines. ( Browning, M; Houghton, PJ; Jackson, SJ; Photiou, A; Retsas, S; Shah, P; Uddin, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shankar Babu, M | 1 |
| Mahanta, S | 1 |
| Lakhter, AJ | 1 |
| Hato, T | 1 |
| Paul, S | 1 |
| Naidu, SR | 1 |
| Houghton, PJ | 1 |
| Photiou, A | 1 |
| Uddin, S | 1 |
| Shah, P | 1 |
| Browning, M | 1 |
| Jackson, SJ | 1 |
| Retsas, S | 1 |
2 other studies available for lapachol and Melanoma
| Article | Year |
|---|---|
Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitor | 2018 |
Activity of extracts of Kigelia pinnata against melanoma and renal carcinoma cell lines.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Renal Cell; Cell Line; Humans; Kidney Neoplasms; Melan | 1994 |