lapachol has been researched along with Malaria, Falciparum in 3 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, ME | 1 |
| Parrott, EE | 1 |
| Singh, R | 1 |
| Nelson, SW | 1 |
| Patel, OPS | 1 |
| Beteck, RM | 1 |
| Legoabe, LJ | 1 |
| Sharma, A | 1 |
| Santos, IO | 1 |
| Gaur, P | 1 |
| Ferreira, VF | 1 |
| Garcia, CR | 1 |
| da Rocha, DR | 1 |
1 review available for lapachol and Malaria, Falciparum
| Article | Year |
|---|---|
Antimalarial application of quinones: A recent update.
Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic | 2021 |
2 other studies available for lapachol and Malaria, Falciparum
| Article | Year |
|---|---|
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle | 2014 |
Addition of thiols to o-quinone methide: new 2-hydroxy-3-phenylsulfanylmethyl[1,4]naphthoquinones and their activity against the human malaria parasite Plasmodium falciparum (3D7).
Topics: Antimalarials; Cells, Cultured; Flow Cytometry; Humans; Indolequinones; Malaria, Falciparum; Molecul | 2013 |