lapachol has been researched along with Leishmania Infection in 1 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leishmaniasis affects more than 12 million people in 98 countries, the infection being caused by more than 20 species of protozoan parasites belonging to the genus Leishmania and spread by sandflies bite." | 2.52 | Topoisomerase 1B as a target against leishmaniasis. ( Castelli, S; D'Annessa, I; Desideri, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Annessa, I | 1 |
| Castelli, S | 1 |
| Desideri, A | 1 |
1 review available for lapachol and Leishmania Infection
| Article | Year |
|---|---|
Topoisomerase 1B as a target against leishmaniasis.
Topics: Antiprotozoal Agents; Camptothecin; DNA Topoisomerases, Type I; Humans; Indoles; Isoquinolines; Leis | 2015 |