Page last updated: 2024-10-30

lapachol and Innate Inflammatory Response

lapachol has been researched along with Innate Inflammatory Response in 4 studies

lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.

Research Excerpts

ExcerptRelevanceReference
"treated with lapachol and [Bi(Lp)(2)]Cl while in the per os treatment inhibition was observed only for [Bi(Lp)(2)]Cl."1.38Coordination of lapachol to bismuth(III) improves its anti-inflammatory and anti-angiogenic activities. ( Andrade, SP; Beraldo, H; Campos, PP; Duarte, LP; Parrilha, GL; Silva, GD; Vieira, RP, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Riça, IG1
Netto, CD1
Rennó, MN1
Abreu, PA1
Costa, PRR1
da Silva, AJM1
Cavalcante, MCM1
Foulkes, MJ1
Tolliday, FH1
Henry, KM1
Renshaw, SA1
Jones, S1
Parrilha, GL1
Vieira, RP1
Campos, PP1
Silva, GD1
Duarte, LP1
Andrade, SP1
Beraldo, H1
Lira, AA1
Sester, EA1
Carvalho, AL1
Strattmann, RR1
Albuquerque, MM1
Wanderley, AG1
Santana, DP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Arm, Open-label Pilot Trial Examining the Effects of Pau d' Arco on Primary Dysmenorrhea in Reproductive Age Women[NCT04245540]Early Phase 112 participants (Actual)Interventional2019-07-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for lapachol and Innate Inflammatory Response

ArticleYear
Anti-inflammatory properties of pterocarpanquinone LQB-118 in mice.
    Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Hydrogen Bonding; Inflammation; Lung Dise

2016
Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish.
    PloS one, 2020, Volume: 15, Issue:10

    Topics: Abietanes; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Apoptosi

2020
Coordination of lapachol to bismuth(III) improves its anti-inflammatory and anti-angiogenic activities.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2012, Volume: 25, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Bismuth; Implants, Experimental; Inflamm

2012
Development of lapachol topical formulation: anti-inflammatory study of a selected formulation.
    AAPS PharmSciTech, 2008, Volume: 9, Issue:1

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Diffusion; Drug Carriers; Drug Compounding;

2008