lapachol has been researched along with Infections, Plasmodium in 1 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Excerpt | Relevance | Reference |
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"The antimalarial activity of benzo[a]phenazines synthesized from 1,2-naphthoquinone, lapachol, beta-lapachone and several derivatives have been tested against Plasmodium falciparum in vitro using isolates of parasites with various susceptibilities to chloroquine and/or mefloquine." | 7.72 | Antimalarial activity of phenazines from lapachol, beta-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo. ( Carvalho, LH; da Silva Filho, JF; da Silva, MJ; de Andrade-Neto, VF; Goulart, MO; Krettli, AU; Pinto, AV; Pinto, Mdo C; Zalis, MG, 2004) |
"The antimalarial activity of benzo[a]phenazines synthesized from 1,2-naphthoquinone, lapachol, beta-lapachone and several derivatives have been tested against Plasmodium falciparum in vitro using isolates of parasites with various susceptibilities to chloroquine and/or mefloquine." | 3.72 | Antimalarial activity of phenazines from lapachol, beta-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo. ( Carvalho, LH; da Silva Filho, JF; da Silva, MJ; de Andrade-Neto, VF; Goulart, MO; Krettli, AU; Pinto, AV; Pinto, Mdo C; Zalis, MG, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
de Andrade-Neto, VF | 1 |
Goulart, MO | 1 |
da Silva Filho, JF | 1 |
da Silva, MJ | 1 |
Pinto, Mdo C | 1 |
Pinto, AV | 1 |
Zalis, MG | 1 |
Carvalho, LH | 1 |
Krettli, AU | 1 |
1 other study available for lapachol and Infections, Plasmodium
Article | Year |
---|---|
Antimalarial activity of phenazines from lapachol, beta-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Malaria; Mice; Naphthoquinones; Phenazines | 2004 |