lapachol and Glioma
lapachol has been researched along with Glioma in 1 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats." | 7.83 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016) |
| "The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats." | 3.83 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Xu, H | 1 |
| Chen, Q | 1 |
| Wang, H | 1 |
| Xu, P | 1 |
| Yuan, R | 1 |
| Li, X | 1 |
| Bai, L | 1 |
| Xue, M | 1 |
Other Studies
1 other study available for lapachol and Glioma
| Article | Year |
|---|---|
Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C | 2016 |