Page last updated: 2024-10-30

lapachol and Glioma

lapachol has been researched along with Glioma in 1 studies

lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats."7.83Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016)
"The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats."3.83Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, H1
Chen, Q1
Wang, H1
Xu, P1
Yuan, R1
Li, X1
Bai, L1
Xue, M1

Other Studies

1 other study available for lapachol and Glioma

ArticleYear
Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II.
    Journal of experimental & clinical cancer research : CR, 2016, 11-16, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2016