lapachol has been researched along with Esophageal Squamous Cell Carcinoma in 1 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Esophageal Squamous Cell Carcinoma: A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lapachol is a 1,4-naphthoquinone that is isolated from the Bignoniaceae family." | 5.51 | Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells. ( Bode, AM; Dong, Z; Kim, DJ; Liu, K; Xie, X; Zhang, Y; Zu, X, 2019) |
| "Lapachol is a 1,4-naphthoquinone that is isolated from the Bignoniaceae family." | 1.51 | Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells. ( Bode, AM; Dong, Z; Kim, DJ; Liu, K; Xie, X; Zhang, Y; Zu, X, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zu, X | 1 |
| Xie, X | 1 |
| Zhang, Y | 1 |
| Liu, K | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Kim, DJ | 1 |
1 other study available for lapachol and Esophageal Squamous Cell Carcinoma
| Article | Year |
|---|---|
Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Esophageal Squam | 2019 |