lapachol has been researched along with Cicatrix, Hypertrophic in 1 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Cicatrix, Hypertrophic: An elevated scar, resembling a KELOID, but which does not spread into surrounding tissues. It is formed by enlargement and overgrowth of cicatricial tissue and regresses spontaneously.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lapachol treatment also inhibited COL1A1 and PAI-1 mRNA levels in hypertrophic scar fibroblasts, but did not affect IL-6 mRNA levels." | 1.37 | Lapachol suppresses cell proliferation and secretion of interleukin-6 and plasminogen activator inhibitor-1 of fibroblasts derived from hypertrophic scars. ( Furukawa, H; Ito, C; Itoigawa, M; Matsui, T; Oda, M; Okada, T; Yokoo, K, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsui, T | 1 |
| Ito, C | 1 |
| Oda, M | 1 |
| Itoigawa, M | 1 |
| Yokoo, K | 1 |
| Okada, T | 1 |
| Furukawa, H | 1 |
1 other study available for lapachol and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Lapachol suppresses cell proliferation and secretion of interleukin-6 and plasminogen activator inhibitor-1 of fibroblasts derived from hypertrophic scars.
Topics: Avicennia; Biopsy; Cell Cycle; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Collagen | 2011 |