lapachol has been researched along with Brain Neoplasms in 2 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats." | 7.83 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016) |
| "The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats." | 3.83 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romão, L | 1 |
| do Canto, VP | 1 |
| Netz, PA | 1 |
| Moura-Neto, V | 1 |
| Pinto, ÂC | 1 |
| Follmer, C | 1 |
| Xu, H | 1 |
| Chen, Q | 1 |
| Wang, H | 1 |
| Xu, P | 1 |
| Yuan, R | 1 |
| Li, X | 1 |
| Bai, L | 1 |
| Xue, M | 1 |
2 other studies available for lapachol and Brain Neoplasms
| Article | Year |
|---|---|
Conjugation with polyamines enhances the antitumor activity of naphthoquinones against human glioblastoma cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Astrocyte | 2018 |
Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C | 2016 |