lapachol has been researched along with Benign Neoplasms, Brain in 2 studies
lapachol : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats." | 7.83 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016) |
| "The antitumor effect of lapachol was firstly evaluated in the C6 glioma model in Wistar rats." | 3.83 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II. ( Bai, L; Chen, Q; Li, X; Wang, H; Xu, H; Xu, P; Xue, M; Yuan, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romão, L | 1 |
| do Canto, VP | 1 |
| Netz, PA | 1 |
| Moura-Neto, V | 1 |
| Pinto, ÂC | 1 |
| Follmer, C | 1 |
| Xu, H | 1 |
| Chen, Q | 1 |
| Wang, H | 1 |
| Xu, P | 1 |
| Yuan, R | 1 |
| Li, X | 1 |
| Bai, L | 1 |
| Xue, M | 1 |
2 other studies available for lapachol and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Conjugation with polyamines enhances the antitumor activity of naphthoquinones against human glioblastoma cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Astrocyte | 2018 |
Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C | 2016 |