lansoprazole has been researched along with Tuberculosis, Multidrug-Resistant in 2 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rybniker, J | 2 |
| Kohl, TA | 1 |
| Barilar, I | 1 |
| Niemann, S | 1 |
| Vocat, A | 1 |
| Sala, C | 1 |
| Busso, P | 1 |
| Pojer, F | 1 |
| Benjak, A | 1 |
| Cole, ST | 1 |
2 other studies available for lansoprazole and Tuberculosis, Multidrug-Resistant
| Article | Year |
|---|---|
No Evidence for Acquired Mutations Associated with Cytochrome
Topics: Antitubercular Agents; Electron Transport Complex III; Humans; Lansoprazole; Microbial Sensitivity T | 2019 |
Lansoprazole is an antituberculous prodrug targeting cytochrome bc1.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Antitubercular Agents; Cell Line; Drug Discovery; | 2015 |