lansoprazole has been researched along with Pregnancy in 11 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients treated for cholestasis or liver diseases were removed." | 5.51 | Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin. ( Abagyan, R; Dai, W; Dong, M; Shi, D; Zhang, Y, 2019) |
| "We followed up 295 pregnancies exposed to omeprazole [233 in the first trimester (T1)], 62 to lansoprazole (55 in T1) and 53 to pantoprazole (47 in T1), and compared pregnancy outcome to that of 868 European Network of Teratology Information Services controls." | 5.11 | The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study. ( Arnon, J; Clementi, M; De Santis, M; Diav-Citrin, O; Malm, H; Ornoy, A; Robert-Gnansia, E; Schaefer, C; Shechtman, S; Valti, E; van Tonningen, MR, 2005) |
| "Although bismuth was both the first drug shown to alter the natural history of peptic ulcer disease and also a constituent of the first very effective eradication regimens, it has been excluded from the newer regimens, despite its safety and low cost, in favour of two antibiotics." | 5.08 | Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication. ( Scott, BB, 1998) |
| " In the present article, the adverse effects of PPIs are reviewed, with special emphasis on those related to their continued administration and on the special circumstances of patients, as in the case of the elderly, those with liver failure, pregnant and breastfeeding mothers and children." | 2.43 | [Safety of proton pump inhibitors]. ( Esplugues, JV; Martí-Cabrera, M; Ponce, J, 2006) |
| "Patients treated for cholestasis or liver diseases were removed." | 1.51 | Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin. ( Abagyan, R; Dai, W; Dong, M; Shi, D; Zhang, Y, 2019) |
| " Rates of congenital malformations in PPIs exposed and unexposed pregnancies, as well as other adverse fetal effects were compared." | 1.38 | The safety of fetal exposure to proton-pump inhibitors during pregnancy. ( Gorodischer, R; Koren, G; Levy, A; Matok, I; Uziel, E; Wiznitzer, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| de Alwis, N | 1 |
| Beard, S | 1 |
| Binder, NK | 1 |
| Pritchard, N | 1 |
| Tong, S | 1 |
| Kaitu'u-Lino, TJ | 1 |
| Hannan, NJ | 1 |
| Le, BL | 1 |
| Iwatani, S | 1 |
| Wong, RJ | 1 |
| Stevenson, DK | 1 |
| Sirota, M | 1 |
| Acar, S | 1 |
| Keskin-Arslan, E | 1 |
| Uysal, N | 1 |
| Karadaş, B | 1 |
| Kaplan, YC | 1 |
| Parton, JR | 1 |
| Ritchie, J | 1 |
| Zhang, Y | 1 |
| Shi, D | 1 |
| Abagyan, R | 1 |
| Dai, W | 1 |
| Dong, M | 1 |
| Terranova, C | 1 |
| Petrella, C | 1 |
| Improta, G | 1 |
| Severini, C | 1 |
| Signore, F | 1 |
| Damiani, P | 1 |
| Plotti, F | 1 |
| Scarpignato, C | 1 |
| Angioli, R | 1 |
| Matok, I | 1 |
| Levy, A | 1 |
| Wiznitzer, A | 1 |
| Uziel, E | 1 |
| Koren, G | 1 |
| Gorodischer, R | 1 |
| Diav-Citrin, O | 1 |
| Arnon, J | 1 |
| Shechtman, S | 1 |
| Schaefer, C | 1 |
| van Tonningen, MR | 1 |
| Clementi, M | 1 |
| De Santis, M | 1 |
| Robert-Gnansia, E | 1 |
| Valti, E | 1 |
| Malm, H | 1 |
| Ornoy, A | 1 |
| Esplugues, JV | 1 |
| Martí-Cabrera, M | 1 |
| Ponce, J | 1 |
| Mayer, A | 1 |
| Sheiner, E | 1 |
| Holcberg, G | 1 |
| Scott, BB | 1 |
1 review available for lansoprazole and Pregnancy
| Article | Year |
|---|---|
[Safety of proton pump inhibitors].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Age Factors; Aged; Animal | 2006 |
2 trials available for lansoprazole and Pregnancy
| Article | Year |
|---|---|
The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abnormalities, Drug-Induced; Adult; Anti-Ulcer Agents; Benz | 2005 |
Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; | 1998 |
8 other studies available for lansoprazole and Pregnancy
| Article | Year |
|---|---|
Placental DAAM2 is unaltered in preeclampsia, but upregulated by treatment with proton pump inhibitors.
Topics: Antioxidants; Esomeprazole; Female; Humans; Hypoxia; Infant, Newborn; Lansoprazole; Microfilament Pr | 2022 |
Computational discovery of therapeutic candidates for preventing preterm birth.
Topics: Computational Biology; Drug Repositioning; Female; Fetus; Humans; Infant, Newborn; Lansoprazole; Pre | 2020 |
Letter: safety of proton pump inhibitors during pregnancy.
Topics: Female; Humans; Lansoprazole; Pregnancy; Proton Pump Inhibitors | 2020 |
Acute upper gastrointestinal bleed in the puerperium following weight reduction surgery.
Topics: Acute Disease; Adult; Bariatric Surgery; Female; Gastrointestinal Hemorrhage; Gastroscopy; Humans; I | 2020 |
Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin.
Topics: Adolescent; Adult; Amoxicillin; Child; Cholestasis; Drug Therapy, Combination; Female; Humans; Lanso | 2019 |
Relaxant effect of proton pump inhibitors on in vitro myometrium from pregnant women.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Apamin; Calcium; Dinoprostone; Esomeprazole; Female; Humans | 2014 |
The safety of fetal exposure to proton-pump inhibitors during pregnancy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abnormalities, Drug-Induced; Adult; Cohort Studies; Databas | 2012 |
Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Female; Gastrinoma; Gastrins; Hum | 2007 |