Page last updated: 2024-10-30

lansoprazole and Neoplasms

lansoprazole has been researched along with Neoplasms in 5 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"The treatment of human cancer has been seriously hampered for decades by resistance to chemotherapeutic drugs."2.79High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors. ( Buglioni, S; Carocci, F; Fais, S; Fanciulli, M; Francesco, M; Spugnini, EP; Vincenzi, B, 2014)
"The treatment of human cancer has been seriously hampered for decades by resistance to chemotherapeutic drugs."2.76Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors. ( Baldi, A; Betti, G; Buglioni, S; Carocci, F; Citro, G; de Bazzichini, GM; Fais, S; Menicagli, F; Pantaleo, I; Spugnini, EP, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Takeda, A1
Takano, N1
Kokuba, H1
Hino, H1
Moriya, S1
Abe, A1
Hiramoto, M1
Tsukahara, K1
Miyazawa, K1
Spugnini, EP2
Buglioni, S2
Carocci, F2
Francesco, M1
Vincenzi, B1
Fanciulli, M1
Fais, S2
Baldi, A1
de Bazzichini, GM1
Betti, G1
Pantaleo, I1
Menicagli, F1
Citro, G1

Reviews

1 review available for lansoprazole and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015

Trials

2 trials available for lansoprazole and Neoplasms

ArticleYear
High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors.
    Journal of translational medicine, 2014, Aug-21, Volume: 12

    Topics: Administration, Metronomic; Animals; Cat Diseases; Cats; Cyclophosphamide; Dog Diseases; Dogs; Dose-

2014
Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors.
    Journal of translational medicine, 2011, Dec-28, Volume: 9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Antineoplastic Agents; Cats; Compassionate Use Tri

2011

Other Studies

2 other studies available for lansoprazole and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization‑associated cell death.
    International journal of oncology, 2020, Volume: 57, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy-Related Protein 5; Azithromycin; Cell Deat

2020