Page last updated: 2024-10-30

lansoprazole and Nausea

lansoprazole has been researched along with Nausea in 10 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."6.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
" pylori-positive peptic ulcer received lansoprazole 30 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 250 mg twice daily for 5 days."5.08Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough? ( Cunnane, K; Kelly, S; Laundon, J; McLoughlin, R; O'Connor, HJ, 1998)
"Although bismuth was both the first drug shown to alter the natural history of peptic ulcer disease and also a constituent of the first very effective eradication regimens, it has been excluded from the newer regimens, despite its safety and low cost, in favour of two antibiotics."5.08Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication. ( Scott, BB, 1998)
" The most common adverse events of headache, diarrhea, and nausea have been reported in fewer than 5% of patients treated with lansoprazole or omeprazole."4.80Safety profile of the proton-pump inhibitors. ( Reilly, JP, 1999)
" Side-effect profile and tolerability were assessed using a symptom-based questionnaire."2.73Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. ( Cindoruk, M; Dursun, A; Erkan, G; Karakan, T; Unal, S, 2007)
"Clarithromycin resistance was indirectly assessed by the (13)C-urea breath test, with a post-treatment value cut-off point at 15."2.73Levofloxacin-containing triple therapy to eradicate the persistent H. pylori after a failed conventional triple therapy. ( Chang, WL; Chen, WY; Cheng, HC; Sheu, BS; Wu, JJ; Yang, HB, 2007)
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."2.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
"Omeprazole was used in 90% of the patients; lansoprazole, in 7%."1.34Characteristics of children receiving proton pump inhibitors continuously for up to 11 years duration. ( El-Serag, HB; Hassall, E; Kerr, W, 2007)
"Lansoprazole was mostly prescribed in patients with reflux oesophagitis (55."1.30A prospective follow-up study of 5669 users of lansoprazole in daily practice. ( Claessens, A; Heerdink, E; Lamers, CB; Leufkens, H; van Eijk, J, 1997)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's4 (40.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kajihara, Y1
Auesomwang, C1
Maneerattanaporn, M1
Chey, WD1
Kiratisin, P1
Leelakusolwong, S1
Tanwandee, T1
Vakily, M1
Amer, F1
Kukulka, MJ1
Andhivarothai, N1
Hassall, E1
Kerr, W1
El-Serag, HB1
Cindoruk, M1
Erkan, G1
Karakan, T1
Dursun, A1
Unal, S1
Cheng, HC1
Chang, WL1
Chen, WY1
Yang, HB1
Wu, JJ1
Sheu, BS1
Leufkens, H1
Claessens, A1
Heerdink, E1
van Eijk, J1
Lamers, CB1
O'Connor, HJ1
McLoughlin, R1
Kelly, S1
Laundon, J1
Cunnane, K1
Scott, BB1
Reilly, JP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Open Labeled Clinical Trial: a Comparative Study of 10-day High Dose PPI-based Triple Therapy vs. 10-day Sequential Therapy for Helicobacter Pylori Eradication in Functional Dyspepsia Patients[NCT01888237]Phase 4118 participants (Actual)Interventional2013-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lansoprazole and Nausea

ArticleYear
Safety profile of the proton-pump inhibitors.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Dec-01, Volume: 56, Issue:23 Suppl 4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Diarrhea; Drug Interactions; Gastric Muc

1999

Trials

6 trials available for lansoprazole and Nausea

ArticleYear
Ten-day high-dose proton pump inhibitor triple therapy versus sequential therapy for Helicobacter pylori eradication.
    Journal of gastroenterology and hepatology, 2018, Volume: 33, Issue:11

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Dizziness; Drug Therapy, Combinatio

2018
Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents

2005
Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study.
    Helicobacter, 2007, Volume: 12, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Clarithromycin; Diarrhea; Double-

2007
Levofloxacin-containing triple therapy to eradicate the persistent H. pylori after a failed conventional triple therapy.
    Helicobacter, 2007, Volume: 12, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin;

2007
Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough?
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial

1998
Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over;

1998

Other Studies

3 other studies available for lansoprazole and Nausea

ArticleYear
An elderly woman with progressive odynophagia, epigastralgia and nausea.
    European journal of internal medicine, 2018, Volume: 57

    Topics: Abdominal Pain; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Endoscopy, Digesti

2018
Characteristics of children receiving proton pump inhibitors continuously for up to 11 years duration.
    The Journal of pediatrics, 2007, Volume: 150, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Distribution; Child; Child, Preschool; Cohort Studies;

2007
A prospective follow-up study of 5669 users of lansoprazole in daily practice.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen

1997