lansoprazole has been researched along with Melanoma in 3 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combination of Lansoprazole (LAN) and CA IX inhibitors (FC9-399A and S4) has been investigated in terms of cell proliferation inhibition and cell death in human melanoma cells." | 7.83 | Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. ( Azzarito, T; Carta, F; Fais, S; Federici, C; Iessi, E; Lugini, L; Marino, ML; Supuran, CT, 2016) |
| " The main purpose of the present study was to evaluate the possible PPI-induced sensitization of human melanoma cells to Paclitaxel (PTX)." | 7.81 | Lansoprazole induces sensitivity to suboptimal doses of paclitaxel in human melanoma. ( Azzarito, T; Cesolini, A; Fais, S; Venturi, G, 2015) |
| "The combination of Lansoprazole (LAN) and CA IX inhibitors (FC9-399A and S4) has been investigated in terms of cell proliferation inhibition and cell death in human melanoma cells." | 3.83 | Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. ( Azzarito, T; Carta, F; Fais, S; Federici, C; Iessi, E; Lugini, L; Marino, ML; Supuran, CT, 2016) |
| " The main purpose of the present study was to evaluate the possible PPI-induced sensitization of human melanoma cells to Paclitaxel (PTX)." | 3.81 | Lansoprazole induces sensitivity to suboptimal doses of paclitaxel in human melanoma. ( Azzarito, T; Cesolini, A; Fais, S; Venturi, G, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azzarito, T | 2 |
| Venturi, G | 1 |
| Cesolini, A | 1 |
| Fais, S | 3 |
| Federici, C | 2 |
| Lugini, L | 2 |
| Marino, ML | 1 |
| Carta, F | 1 |
| Iessi, E | 2 |
| Supuran, CT | 1 |
| Sciamanna, I | 1 |
| Spugnini, EP | 1 |
3 other studies available for lansoprazole and Melanoma
| Article | Year |
|---|---|
Lansoprazole induces sensitivity to suboptimal doses of paclitaxel in human melanoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Drug Resistance, Neoplasm | 2015 |
Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Cel | 2016 |
Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase.
Topics: Alkynes; Antineoplastic Combined Chemotherapy Protocols; Benzoxazines; Cell Line, Tumor; Cell Prolif | 2017 |