lansoprazole has been researched along with Long QT Syndrome in 4 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Combination therapy of ceftriaxone and lansoprazole is associated with increased risk of acquired long QT syndrome." | 3.83 | Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation. ( Chang, JB; Iyer, V; Kass, RS; Lorberbaum, T; Sampson, KJ; Tatonetti, NP; Woosley, RL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lazzerini, PE | 1 |
| Bertolozzi, I | 1 |
| Rossi, M | 1 |
| Capecchi, PL | 1 |
| Laghi-Pasini, F | 1 |
| Lorberbaum, T | 2 |
| Tatonetti, NP | 2 |
| Sampson, KJ | 1 |
| Chang, JB | 1 |
| Iyer, V | 1 |
| Woosley, RL | 1 |
| Kass, RS | 1 |
| Asajima, H | 1 |
| Saito, N | 1 |
| Ohmura, Y | 1 |
| Ohmura, K | 1 |
4 other studies available for lansoprazole and Long QT Syndrome
| Article | Year |
|---|---|
Combination Therapy With Ceftriaxone and Lansoprazole, Acquired Long QT Syndrome, and Torsades de Pointes Risk.
Topics: Ceftriaxone; Data Mining; Drug Interactions; Electrocardiography; Humans; Lansoprazole; Long QT Synd | 2017 |
Reply: Combination Therapy With Ceftriaxone and Lansoprazole, Acquired Long QT Syndrome and Torsades de Pointes Risk.
Topics: Ceftriaxone; Electrocardiography; Humans; Lansoprazole; Long QT Syndrome; Torsades de Pointes | 2017 |
Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation.
Topics: Aged; Ceftriaxone; Cefuroxime; Data Mining; Drug Interactions; Drug-Related Side Effects and Adverse | 2016 |
Lansoprazole precipitated QT prolongation and torsade de pointes associated with disopyramide.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Arrhythmia Agents; Anti-Ulcer Agents; Disopyrami | 2012 |