Page last updated: 2024-10-30

lansoprazole and Local Neoplasm Recurrence

lansoprazole has been researched along with Local Neoplasm Recurrence in 4 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Research Excerpts

ExcerptRelevanceReference
"In this phase 3, randomized (1:1), double-blind, double-dummy, parallel-group, non-inferiority study (April 5, 2017, to July 19, 2019), patients with ≥ 1 endoscopically confirmed duodenal ulcer, at 52 hospitals (China, South Korea, and Taiwan), received vonoprazan 20 mg once daily (QD) or lansoprazole 30 mg QD for 6 weeks maximum."9.51Vonoprazan non-inferior to lansoprazole in treating duodenal ulcer and eradicating Helicobacter pylori in Asian patients. ( Chiu, CT; Chong, CF; Chung, WC; Gu, L; Hou, X; Kudou, K; Meng, F; Sha, W; Wang, J; Zhang, S, 2022)
"In this phase 3, randomized (1:1), double-blind, double-dummy, parallel-group, non-inferiority study (April 5, 2017, to July 19, 2019), patients with ≥ 1 endoscopically confirmed duodenal ulcer, at 52 hospitals (China, South Korea, and Taiwan), received vonoprazan 20 mg once daily (QD) or lansoprazole 30 mg QD for 6 weeks maximum."5.51Vonoprazan non-inferior to lansoprazole in treating duodenal ulcer and eradicating Helicobacter pylori in Asian patients. ( Chiu, CT; Chong, CF; Chung, WC; Gu, L; Hou, X; Kudou, K; Meng, F; Sha, W; Wang, J; Zhang, S, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Hou, X1
Meng, F1
Wang, J1
Sha, W1
Chiu, CT1
Chung, WC1
Gu, L1
Kudou, K1
Chong, CF1
Zhang, S1
Tuyaerts, S1
Van Nuffel, AMT1
Naert, E1
Van Dam, PA1
Vuylsteke, P1
De Caluwé, A1
Aspeslagh, S1
Dirix, P1
Lippens, L1
De Jaeghere, E1
Amant, F1
Vandecasteele, K1
Denys, H1
Fukase, K1
Kato, M1
Kikuchi, S1
Inoue, K1
Uemura, N1
Okamoto, S1
Terao, S1
Amagai, K1
Hayashi, S1
Asaka, M1
Hamaguchi, K1
Ogawa, K1
Katsube, T1
Konno, S1
Aiba, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Investigation of Pembrolizumab (Keytruda) in Combination With Radiation and an Immune Modulatory Cocktail in Patients With Cervical and Uterine Cancer (PRIMMO Trial)[NCT03192059]Phase 243 participants (Actual)Interventional2017-07-01Completed
Prediction for the Development of Metachronous Gastric Cancer After Endoscopic Submucosal Dissection by Serum Pepsinogen[NCT02682446]800 participants (Actual)Observational2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for lansoprazole and Local Neoplasm Recurrence

ArticleYear
Vonoprazan non-inferior to lansoprazole in treating duodenal ulcer and eradicating Helicobacter pylori in Asian patients.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:7

    Topics: Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Drug Therapy, Combination; Duod

2022
PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer.
    BMC cancer, 2019, May-28, Volume: 19, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspirin; Chemoradiotherapy; Curcumin; Cycl

2019
Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial.
    Lancet (London, England), 2008, Aug-02, Volume: 372, Issue:9636

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Clarithromycin; Endoscopy, Gas

2008

Other Studies

1 other study available for lansoprazole and Local Neoplasm Recurrence

ArticleYear
Does eradication of Helicobacter pylori reduce the risk of carcinogenesis in the residual stomach after gastrectomy for early gastric cancer? Comparison of mucosal lesions in the residual stomach before and after Helicobacter pylori eradication.
    Langenbeck's archives of surgery, 2004, Volume: 389, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Aged; Amoxicillin; Anti-Bacterial Agents; A

2004