Page last updated: 2024-10-30

lansoprazole and Laryngeal Diseases

lansoprazole has been researched along with Laryngeal Diseases in 7 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Laryngeal Diseases: Pathological processes involving any part of the LARYNX which coordinates many functions such as voice production, breathing, swallowing, and coughing.

Research Excerpts

ExcerptRelevanceReference
"The association of gastroesophageal reflux disease (GERD) and laryngeal symptoms is not clear."2.78Is the proton pump inhibitor test helpful in patients with laryngeal symptoms? ( Hong, SN; Kim, JH; Lee, SY; Park, HS; Shim, CS; Sung, IK, 2013)
" Results were further analyzed to compare failure rates based on different dosage regimens."1.31Proton pump inhibitor resistance in the treatment of laryngopharyngeal reflux. ( Amin, MR; Digges, N; Johnson, P; Koufman, JA; Postma, GN, 2001)
"Gastroesophageal reflux, common in infants, usually resolves spontaneously by 12 to 18 months."1.31[Laryngeal manifestations of gastroesophageal reflux disease (GERD) in pediatric patients: the usefulness of therapeutic (proton pump inhibitor (PPI)) trials]. ( Niimi, S; Saigusa, H; Saigusa, U; Yagi, T, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, JH1
Sung, IK1
Hong, SN1
Lee, SY1
Park, HS1
Shim, CS1
Lee, YC1
Na, SY1
Kim, HJ1
Yang, CW1
Kim, SI1
Byun, YS1
Jung, AR1
Ryu, IY1
Eun, YG1
Hill, RK1
Simpson, CB1
Velazquez, R1
Larson, N1
Silvers, WS1
Levine, JS1
Poole, JA1
Naar, E1
Weber, RW1
Belafsky, PC1
Postma, GN2
Koufman, JA2
Amin, MR1
Johnson, P1
Digges, N1
Saigusa, H1
Niimi, S1
Saigusa, U1
Yagi, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265]Phase 418 participants (Actual)Interventional2006-08-31Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.)
A Prospective Evaluation of the Utility, Optimal Cutoff and Positive Predictive Value of a Pharyngeal pH Probe for Predicting Proton Pump Inhibitor Response in Treatment Naive Laryngopharyngeal Reflux[NCT01755221]80 participants (Anticipated)Interventional2012-08-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for lansoprazole and Laryngeal Diseases

ArticleYear
Is the proton pump inhibitor test helpful in patients with laryngeal symptoms?
    Digestive diseases and sciences, 2013, Volume: 58, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Drug Administration Sche

2013
Effect of postoperative proton pump inhibitor therapy on voice outcomes following phonomicrosurgery for vocal fold polyp: a randomized controlled study.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2016, Volume: 41, Issue:6

    Topics: Adult; Female; Humans; Lansoprazole; Laryngeal Diseases; Laryngoscopy; Male; Microsurgery; Middle Ag

2016

Other Studies

5 other studies available for lansoprazole and Laryngeal Diseases

ArticleYear
Pachydermia is not diagnostic of active laryngopharyngeal reflux disease.
    The Laryngoscope, 2004, Volume: 114, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

2004
Inlet patch of gastric mucosa in upper esophagus causing chronic cough and vocal cord dysfunction.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Androstadienes; Anti-Allergic Agents; Cough; Endoscopy, Gas

2006
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Proton pump inhibitor resistance in the treatment of laryngopharyngeal reflux.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2001, Volume: 125, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans;

2001
[Laryngeal manifestations of gastroesophageal reflux disease (GERD) in pediatric patients: the usefulness of therapeutic (proton pump inhibitor (PPI)) trials].
    Nihon Jibiinkoka Gakkai kaiho, 2001, Volume: 104, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Child; Child, Preschool; Gastroesophageal Reflux; Humans; I

2001