Page last updated: 2024-10-30

lansoprazole and Hypotension, Orthostatic

lansoprazole has been researched along with Hypotension, Orthostatic in 1 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.

Research Excerpts

ExcerptRelevanceReference
" An open-label, randomized, crossover, phase I, pharmacokinetic interaction design was used."2.72Lack of pharmacokinetic interaction between omeprazole or lansoprazole and ivabradine in healthy volunteers: an open-label, randomized, crossover, pharmacokinetic interaction clinical trial. ( Calvo, A; Gorostiaga, C; Laredo, L; Moreno, A; Portolés, A; Resplandy, G; Terleira, A, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Portolés, A1
Calvo, A1
Terleira, A1
Laredo, L1
Resplandy, G1
Gorostiaga, C1
Moreno, A1

Trials

1 trial available for lansoprazole and Hypotension, Orthostatic

ArticleYear
Lack of pharmacokinetic interaction between omeprazole or lansoprazole and ivabradine in healthy volunteers: an open-label, randomized, crossover, pharmacokinetic interaction clinical trial.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Anti-Ulcer Agents;

2006